Abstract: Objective To explore the distribution and prevalent trend of clonorchiases and their influencing factors among residents living in endemic areas of Liaoning province for making effective measures to control the disease.Methods The stool specimens were collected among susceptible people in endemic areas of Liaoning province to assess infection of Clonorchis sinensis(C.sinensis) and monitoring on intermediate host of C.sinensis and a face-to-face questionnaine survey was also conducted simultaneously in May to October,2007.Chi-square test and Fisher's exact test were adopted in data analyses.Results The infection rate of C.sinesis was 3.48% among 1 754 residents participating in the survey and the infection rate was significantly different among the residents of different age(χ²=19.99,P=0.010),with the highest rate in the residents aged 71-81 years.There were significant differences in the infection rate among the residents of different nationality(χ²=24.85,P<0.001) and different education level(P<0.01).The highest infection rate of intermediate host was observed in Pseudorasbora parva(54.36%).The residents with different health behavior had different infection rate(P<0.001).Conclusion The results show that the infection rate of C.sinesis is closely related to age,nationality,and education level and Pseudorasbora elongate is the intermediate host with the highest infection rate in endemic areas of clonorchiasis in Liaoing province.