Abstract: ObjectiveTo investigate the compliance of home chemotherapy and its influencing factors among infectious tuberculosis patients.MethodsWe used stratified random sampling to choose 720 infectious tuberculosis patients with home chemotherapy from 6 areas in Shandong province.The investigation was carried out with a self-administered questionnaire to collect information on compliance of home chemotherapy and its influencing factors.ResultsThe patients were 506 men(70.3%)and 214 women(19.7%).Among the patients only 43.9%complied with the home chemotherapy and 56.1%did not comply with the chemotherapy.Compared with the patients of divorced or windowed,the married patients had a better compliance of home chemotherapy (odds ratio OR=0.490,P=0.026).Patients with urban worker's medical insurance had a higher incompliance rate compared with those with new rural cooperative medical system (OR=2.415,P=0.003).The patients registered in rural areas had a higher incompliance compared with those registered in urban areas (OR=2.019 P=0.044).ConclusionMore than a half of the infectious tuberculosis patients in 6 urban and rural areas of Shandong province did not comply with home chemotherapy and marriage status,medical care and registered living areas related to the compliance of home chemotherapy.