Abstract: ObjectiveTo analyze the impact of the implementation of performance-related pay on working enthusiasm among health workers in centers for disease control and prevention(CDCs).MethodsTotally 274 CDCs were selected from the country's 30 provinces or municipalities and Xinjiang Production and Construction Corps(excluding Tibet)with stratified-cluster random sampling and questionnaire surveys were conducted to collect relevant information.Influencing factors of working enthusiasm were analyzed through non-conditional logistic regression method.ResultsAfter implementing performance-related pay,the working enthusiasm in 69.7% of the workers was improved,and there were significant differences in the ratios of workers with increased enthusiasm among the staff of the provincial,municipal and county level CDCs(P=0.04).Univariate analysis showed that significant influencing factors of the workers' enthusiasm were good working environment,good career development,reasonable payment level,training opportunities,reasonable preparation,job promotion opportunities,and taking on important tasks.Multi-factor logistic regression model showed that the factor influencing health workers' enthusiasm was reasonable payment level(odds ratio=5.15)ConclusionThe reasonable level of wages is the key factor affecting the enthusiasm of the health workers in CDCs.