Abstract: Objective To examine prevalence characteristics of diabetes and pre-diabetes among adult residents in Hubei province.Methods A survey including questionnaire interview,physical examination,fasting blood glucose (FBG) detection,oral glucose tolerance test (OGTT) was conducted among 6 000 permanent residents aged ≥ 18 years selected with multistage random cluster sampling from 10 counties or districts in Hubei province in 2013.SAS 9.3 was used in data analysis.Results For the 5 824 residents completing the survey,the average FBG (mmol/L) was 5.46 (95% confidence interval:5.22-5.70) and the average blood glucose (mmol/L) 2 hours after the OGTT was 6.23 (5.89-6.58) after adjustment via post-stratification weighting.The prevalence rate of diabetes was 8.26% (598/5 824) for the all residents,9.79% (262/2 331) and 6.69% (336/3 493) for the male and female residents,and 8.93% (357/3 169) and 7.24% (241/2 655) for the urban and rural residents,respectively;while the self-reported prevalence rate of diabetes was only 2.85% (230/5 822).The prevalence rate of elevated FBG was 5.84% (410/5 824).Among the all residents,the prevalence rate of pre-diabetes,impaired FBG,abnormal OGTT,and impaired FBG complicated with abnormal OGTT were 14.17% (940 cases),5.00% (325),6.64% (467),and 2.54% (148),respectively.There was no gender difference in the prevalence rate of diabetes and pre-diabetes,but the rates upsurged along with the increment of age in the residents (both P<0.01).The urban residents had significantly higher prevalence rate of diabetes (P<0.01)but lower prevalence rate of impaired FBG (P=0.03) than the rural residents.ConclusionThe prevalence rate of diabetes and pre-diabetes showed an upward trend among adult residents in Hubei province.