Abstract:
Objective To compare the correlation of results of HBV DNA by flor escence PCR and HBsAg titer, and to discuss the application of detecting HBV DNA by fluorescent quantitative PCR.
Methods The serum samples from 1 025 HBsAg positive persons applying for service work were tested by FQ-PCR kits and compared with ELISA results and HBsAg titer test.
Results The results of FQ-PCR comparing with ELISA were accord with the general rule.The results of FQ-PCR comparing with HBsAg titer test had nosignificantly relationship.
Conclusion The quantification of HBV DNA can be a reference for anti-virus therapy and evaluation of infectivity.Instead of the HBsAg titer test, workers of food production and sell with HBsAg positive would be better tested on HBV DNA for the application of health certification.