大连地区新生儿弓形虫感染的免疫学检测

Study on status of toxoplasma infection and immunology detection in new-born babies

摘要:
目的探讨大连地区新生儿弓形虫感染的情况。
方法采用酶联免疫吸附试验三联诊断法对93例新生儿脐带血清标本进行弓形虫感染的血清学检测。
结果新生儿弓形虫各单项检测阳性率分别为循环抗原(CAg)4.3%、IgM2.2%、IgG15.1%, 新生儿弓形虫平均感染率为194%, 其中近期感染率为5.4%。
结论新生儿弓形虫感染的危险性很高, 应开展孕妇血清学监测及时采取措施, 有效地预防先天性弓形虫感染。

Abstract:
Objective To investigate the status of toxoplasma(Tox)infection in new-born babies.
Methods Enzymlinked immunosorbent assay(ELISA)was used to detect circulating antigen(CAg), special antibodies IgM and IgG in fetal umbilical blood.
Results Among the 93 cases, 4 were TOX-CAg positive(4.3%), 2 were TOX-IgM positive(2.2%)and 14 were TOX-IgG positive(15.1%)in new born infants.the overall prevalence rate of toxoplasmosis among the new born infants was 19.4% (18/93);the rate of acute infection was 5.4%.
Conclusion New born infants are at the high risk of toxoplasma infection, about 5.4% fetus will get acute infection from their mothers before they give birth.Therefore, Sero-epidemiologic survey in pregnant women show an impor tant sig nificance in better child-bearing.