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刘立军, 刘泽嵚, 张馨, 王伟, 韩驰. 茶叶中维生素和微量元素的防癌作用研究[J]. 中国公共卫生, 2004, 20(10): 1166-1168.
引用本文: 刘立军, 刘泽嵚, 张馨, 王伟, 韩驰. 茶叶中维生素和微量元素的防癌作用研究[J]. 中国公共卫生, 2004, 20(10): 1166-1168.
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LIU Li-jun, LIU Ze-qin, Zhang Xin, . Study on anti-carcinogenic effects of vitamins and trace elements in tea[J]. Chinese Journal of Public Health, 2004, 20(10): 1166-1168.
Citation: LIU Li-jun, LIU Ze-qin, Zhang Xin, . Study on anti-carcinogenic effects of vitamins and trace elements in tea[J]. Chinese Journal of Public Health, 2004, 20(10): 1166-1168.
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茶叶中维生素和微量元素的防癌作用研究

Study on anti-carcinogenic effects of vitamins and trace elements in tea

    摘要
  • 摘要:
      目的   探讨茶叶中维生素和微量元素在茶叶防癌中的作用, 进一步对茶叶防癌有效成分进行筛选。
      方法   应用一组短期细胞学检测试验, 即V79细胞胞质阻滞法微核试验、细胞代谢协作试验和Hela细胞软琼脂生长试验, 筛选茶叶含有的微量元素Zn、Se、Mn、Mo和维生素E、β-胡萝卜素、维生素C的预防肿瘤作用。
      结果   10 -5mol/LZn、Se、Mn、β胡萝卜素, 10 -6, 10 -5mol/L维生素C, 10和20mg/L维生素E对微核的形成具有抑制作用; 10 -5mol/L Se、Mo、β胡萝卜素、维生素C和10, 20mg/L维生素E能抑制Hela细胞软琼脂生长; 7种维生素和微量元素在受试浓度对佛波酯(TPA)抑制的代谢协同作用无显著性影响。
      结论   茶叶中的维生素和微量元素在防癌中不起主要作用。

     

    Abstract:
      Objective   Anti-carcinogenic effects of several vitamins and trace elements in tea were investigated in order to compare the anticar cinogenic effects among the teaingredients.
      Methods   By using several well-established short term, tests i.e, V79 cell cyto kinesis block micronuclei test, V79 cell metabolic cooperation test and Hela cell growth ability test in soft agar, several trace elements including Zn, Se, Mn, Mo and vitamin C, E and B-carotene were used to screen the anticarcinogenic ingredients in the tea.
      Results   Zn, Se, Mn, B-carotene at the concentration of 10 -5 mol/L vitamin C at the concentration of 10 -6 and 10 -5 mol/L, vitamin E at the concentration of 10 and 20 mg/L inhibited the for mation of micronuclei in V79 cells.Se, Mo, B-carotene, vitamin C at the concentration of 10 -5 mol/L, vitamin E at the concentration of 10 and 20 mg/L prevented the Hela cell growth ability in soft agar.However, seven elements had no effect on V79 cell metabolic cooperation inhibited by TPA.
      Conclusion   Tested trace elements and vitamins had anticar cinogenic effects athigh concentrations.But these elements weren't the major anticarcinogenic ingredients in tea.

     

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