深圳市预防与控制梅毒母婴传播实施策略初探
Strategy on syphilis prevention of mother-to-child transmission in Shenzhen
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摘要:目的 探讨阻断梅毒母婴传播和降低新生儿先天梅毒发病的策略, 最大限度地控制和降低先天梅毒的发生。方法 设立专项防治经费, 启动深圳市预防与控制梅毒母婴传播项目, 开展妊娠梅毒免费普查及综合干预工作, 及时发现孕产妇人群中的梅毒感染者, 阻断或降低梅毒母婴传播及新生儿先天梅毒的发生, 并对其进行效果评估及成本效益分析。结果 深圳市预防与控制梅毒母婴传播项目实施以来, 共检测孕妇186517例, 检出梅毒阳性777例, 阳性率4.16‰。对555例孕产妇梅毒患者进行追踪随访, 选择继续妊娠330例, 终止妊娠181例, 失访44例。检测孕产妇梅毒患者所生婴儿126例, 快速血浆反应素环状卡片试验(RPR)初筛阳性109例, 最终确诊先天梅毒24例。项目的实施成功阻断了87.30%产妇梅毒可能造成的母婴传播。2003年深圳市先天梅毒报告24例, 比2002年同期减少39例, 下降61.90%。结论 实施预防与控制梅毒母婴传播项目适合深圳市情, 将为广东省乃至全国探索梅毒防治提供行之有效的策略和经验。Abstract:Objective To explore the strategy on syphilis prevention of mother-to-child transmission and reduction of antenatal syphilis.Methods It was in the form of special funds for syphilis prevention that started-up project of syphilis prevention of mother-to-child transmission in Shenzhen.It should carry out routine screening for syphilis in pregnancy and do much interference among them and detect pregnant women infected syphilis timely and prevent syphilis mother-to-child transmission.By effect evaluation and cost-benefit analysis the project would be proved greatly.Results 186 517 cases were free blood-tested for syphilis and 777 were positve.The prevalence rate were 416.58×10-5.555 pregnant women with syphilis were followed-up after treatment.330 cases were chosen to continue to be pregant and 181 chosed termination of pregnancy and 44 were missed.126 infants were tested for syphilis and 109 cases were positive with RPRscreening and 24 were finally diag nosed.It blocked 87.30% mother-to-child sy philis since the project were done.24 cases were reported antenatal syphilis in 2003 in Shenzhen and decreased 39(61.90%)compared with that in 2002.Conclusion It will come into being that the project adapted to the situation of Shenzhen and provides effective strategy and experience on syphilis prevention in Guangdong province and all over the country.
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