Abstract:
Objective To understand the purity and the impurity of the synthesized ebselen (Ebs) and the acute toxicity.
Methods The Ebs was tested with HPLC, the impurity was detected with chromatometry and the acute test was done by adultratlav aged one time and the 24-hour mortality rate was observed.
Results The purity of Ebs was 99.95%-99.99%, the amount of phenylamine was 0.000 17%-0.000 19%, the LD50 of the rat lavaged by mouth one time was 2 355.05mg/kg.
Conclusion The quality of Ebs was reliable, the security was high, and it could be used for exploitation and study.