T淋巴细胞核仁形成区嗜银蛋白含量的对比

Contrast analysis on containing Ag-NORs in Tlymphocyte of lung cancer and pulimonary tuberculosis

摘要:
目的探讨核仁形成区嗜银蛋白(Ag-NORs)含量检测对肺癌和肺结核患者的诊断及鉴别诊断的意义.
方法采用KL型免疫分析系统检测正常人、肺癌和肺结核患者外周血T淋巴细胞核仁形成区嗜银蛋白含量, 用I.S%表示.以反映T淋巴细胞核内rDNA的转录活性.
结果肺癌患者和肺结核患者的I.S值均明显低于正常人(P < 0.01);肺癌患者的I.S%值显著低于肺结核患者(P < 0.01).
结论 Ag-NORs检测对于鉴别正常人、肺癌、肺结核患者有一定意义.

Abstract:
Objective To explore the significance of the measurement of Ag-NORs(Argyrophilic nucleolar or angizer region proteins)in dist inguishing the patients with lung cancer and pulmonar y tuberculosis.
Methods the KL-immune analysis system was used to analyse Ag-NORs in lymphocyte of the healthy people, patients with lung cancer and pulmonary tuber culosis, which denoted with I.S%.It reflected the rDNA transcription activity in the nuclear of T lymphocyte.
Results the value of I.S% was much lower in patients with lung cancer and tuber culosis than in health people.And obvious differences were found between them(P < 0.01).The lung cancer was much lower than those of tuberculosis patients(P < 0.01).
Conclusion the measurement of Ag-NORs had certain significe in diagnosis and distinguishing the lung cancer and pulmonary tuberculosis patients.