染尘大鼠肺泡灌洗液对人胚肺细胞DNA含量的影响

Effect of Bronchoalveolar Lavage Fluid(BALF) from Rats Expousure to Chrysotile or Silica on DNA Content of Human

摘要: 用流式细胞仪测定了石棉和石英染尘后2个月内大鼠支气管肺泡灌洗液对人胚肺细胞DNA含量水平的影响。结果发现石棉和石英均可引起灌洗液中促进DNA合成物质的含量增加，石棉诱导这种促DNA合成的能力比石英更强、更持久，提示石棉诱导这种生长因子高度的表达，可能在石棉的致肿瘤过程中起一定作用。

Abstract: 3 groups of male Wistar were in tratracherlly in stilled with1ml sailine,Mang-Ya chrysotile suspension(10mg/ml),Rats were sacrificed 30 and 60 days after exposure and the effec.