间接血凝法和动物法测定人血清破伤风抗体的比较

Comparison between Indirect Hemagglutination Method and Animal Inoculation Method for Determination of Anti-tetanus Antibcdy in Human Serum

摘要: 本文报导用间接血凝法和小白鼠中和试验法，同时测定342份人血清破伤风抗体效价。发现两种方法的测定结果密切相关，相关系数（r）为0.88（P<0.0005）。当人血清中破伤风抗体达到间接血凝效价0.156Hu/ml时，即相当于动物法的0.01Iu/ml。认为，间接血凝法快速、简便、经济，可以代替动物试验测定法。

Abstract: Anti-tetanus antibody titers in 342 human serum samples were determined simultaneously by indirect hemagglutination method and neutralization test in mice,The results obtaned by these two methods were found to be closely correlated with a,correlation coefficient (r)of 0.88(p<0.0005).