Abstract: There was a cholera outbreak in 6 counties(cities) situatedat coastal areas in Hainan Province from July to November 1998. A total of 153 cases were fo found, most of which were aged at 20-50, accounting for 55.56%, and the main occupation is peasants(31.37%). The peak of endemic was between August and September, and the ratioo fmale to female is 1:1.04. The result shows that the dominant biotype of vibriocholerae was 1b O gawa, accounting for 98.75%, and the main spread way were food and water. The chole raendemic was controled timely and effectively through wide health eduction, management of food and enviroment and aetiotogical survillance.