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Volume 38 Issue 6
Jun.  2022
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PANG Lin-hong, LU Jiang, SONG Hong-lin, . Impact of delayed diagnosis time on post-surgery recovery in 0 – 18 years old congenital heart disease patients in 8 western provinces of China: a comparative analysis[J]. Chinese Journal of Public Health, 2022, 38(6): 671-675. doi: 10.11847/zgggws1135338
Citation: PANG Lin-hong, LU Jiang, SONG Hong-lin, . Impact of delayed diagnosis time on post-surgery recovery in 0 – 18 years old congenital heart disease patients in 8 western provinces of China: a comparative analysis[J]. Chinese Journal of Public Health, 2022, 38(6): 671-675. doi: 10.11847/zgggws1135338

Impact of delayed diagnosis time on post-surgery recovery in 0 – 18 years old congenital heart disease patients in 8 western provinces of China: a comparative analysis

doi: 10.11847/zgggws1135338
  • Received Date: 2021-05-07
    Available Online: 2021-12-13
  • Publish Date: 2022-06-01
  •   Objective  To explore the association of delayed diagnosis time with post-surgery recovery in children with congenital heart disease (CHD) for providing evidences to effective early screening and treatment of CHD.  Methods  From January 2017 to December 2020, a CHD screening program was conducted among 3 015 470 students from 7 783 schools in 8 provincial-level regions in western China and totally 3 805 diagnosed CHD patients were surgically treated at Fuwai Yunnan Cardiovascular Hospital and followed up for post-treatment management. Medical records and information on physical-psychological-social adaptation of the CHD patients aged 0 – 18 years were collected and analyzed to assess the correlation between delayed diagnosis time and post-surgery recovery in the child patients.  Results  Of the 2 879 child patients included in the analysis, 66.3% (1 908) had delayed diagnosis of CHD and 23.0% (663), 21.4% (615), and 21.9% (630) had delayed diagnosis time of 0.03 – 3 years, 3.01 – 7.5 years, and longer than 7.5 years, respectively. Among the child patients with delayed diagnosis time of 0.03 – 3 years, 19.7% had developmental retardation and 28.0% had difficulty in group living; of the child patients with the delayed diagnosed time longer than 7.5 years, 17.4% were assessed being prone to have negative emotion. After adjusting for gender, age, ethnics, type of CHD, and family structure, the results of multivariate logistic regression analysis demonstrated that compared to those with the delayed diagnosis time of longer than 7.5 years, the child patients with shorter delayed diagnosis time were at a decreased the risk of post-surgery negative emotion with the odds ratio (OR) of 0.685 (95% confidence interval [95% CI]: 0.499 – 0.940) for those with the time of 0.03 – 3 years and the OR of 0.630 (95% CI: 0.450 – 0.882) for those with the time of 3.01 – 7.5 years; while, compared to those with the delayed diagnosis time of 0.03 – 3 years, the child patients being timely diagnosed and the patients with the delayed diagnosis time longer than 7.5 years were at a decreased risk of having difficulty in group living, with the OR of 0.717 (95% CI: 0.563 – 0.914) and OR of 0.685 (95% CI: 0.528 – 0.888), respectively.   Conclusion  Among child patients having surgery treatment, the delayed time of CHD diagnosis can influence post-surgery recovery; the delayed diagnosis time of 7.5 years is associated with the incidence of post-surgery negative emotion and that of 0.03 – 3 years is related to having difficulty in group living after surgery treatment.
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  • [1]
    中国心血管健康与疾病报告编写组. 中国心血管健康与疾病报告2019概要[J]. 中国循环杂志, 2020, 35(9): 833 – 854.
    [2]
    高漫辰, 张凤文, 潘湘斌. 《中国心血管健康与疾病报告2019》先天性心脏病部分解读[J]. 中国胸心血管外科临床杂志, 2021, 28(4): 384 – 387.
    [3]
    李振. 云南省先天性心脏病相关危险因素的病例对照研究[D]. 昆明: 昆明医科大学, 2018.
    [4]
    Castro F, Zúñiga J, Higuera G, et al. Indigenous ethnicity and low maternal education are associated with delayed diagnosis and mortality in infants with congenital heart defects in panama[J]. PLoS One, 2016, 11(9): e0163168. doi: 10.1371/journal.pone.0163168
    [5]
    Rashid U, Qureshi AU, Hyder SN, et al. Pattern of congenital heart disease in a developing country tertiary care center: factors associated with delayed diagnosis[J]. Annals of Pediatric Cardiology, 2016, 9(3): 210 – 215. doi: 10.4103/0974-2069.189125
    [6]
    胡大一. 先心病外科矫治手术的最佳时间[J]. 开卷有益: 求医问药, 2002(9): 8.
    [7]
    Dawson AL, Cassell CH, Riehle-Colarusso T, et al. Factors associated with late detection of critical congenital heart disease in newborns[J]. Pediatrics, 2013, 132(3): e604 – e611. doi: 10.1542/peds.2013-1002
    [8]
    Liberman RF, Getz KD, Lin AE, et al. Delayed diagnosis of critical congenital heart defects: trends and associated factors[J]. Pediatrics, 2014, 134(2): e373 – e381. doi: 10.1542/peds.2013-3949
    [9]
    Brown KL, Ridout DA, Hoskote A, et al. Delayed diagnosis of congenital heart disease worsens preoperative condition and out-come of surgery in neonates[J]. Heart, 2006, 92(9): 1298 – 1302. doi: 10.1136/hrt.2005.078097
    [10]
    Eckersley L, Sadler L, Parry E, et al. Timing of diagnosis affects mortality in critical congenital heart disease[J]. Archives of Disease in Childhood, 2016, 101(6): 516 – 520. doi: 10.1136/archdischild-2014-307691
    [11]
    Opić P, Roos-Hesselink JW, Cuypers JAA, et al. Psychosocial functioning of adults with congenital heart disease: outcomes of a 30 – 43 year longitudinal follow-up[J]. Clinical Research in Cardiology, 2015, 104(5): 388 – 400. doi: 10.1007/s00392-014-0792-1
    [12]
    Perrotti A, Ecarnot F, Monaco F, et al. Quality of life 10 years after cardiac surgery in adults: a long-term follow-up study[J]. Health and Quality of Life Outcome, 2019, 17(1): 88. doi: 10.1186/s12955-019-1160-7
    [13]
    Freitas IR, Castro M, Sarmento SL, et al. A cohort study on psychosocial adjustment and psychopathology in adolescents and young adults with congenital heart disease[J]. BMJ Open, 2013, 3(1): e001138. doi: 10.1136/bmjopen-2012-001138
    [14]
    陈文英, 王艳. 385例胎儿先天性心脏病围生结局及预后分析[J]. 中国妇幼健康研究, 2015, 26(6): 1136 – 1138, 1142. doi: 10.3969/j.issn.1673-5293.2015.06.010
    [15]
    赵璐, 刘芳, 吴琳, 等. 先天性心脏病术后残余室间隔缺损介入治疗及中长期随访[J]. 中国循证儿科杂志, 2014, 9(5): 371 – 376. doi: 10.3969/j.issn.1673-5501.2014.05.009
    [16]
    韩凤珍, 江燕萍, 周成斌, 等. 胎儿先天性心脏病151例围生结局及预后分析[J]. 实用妇产科杂志, 2012, 28(9): 760 – 764. doi: 10.3969/j.issn.1003-6946.2012.09.019
    [17]
    国家卫生计生委妇幼健康服务司,全国妇幼卫生监测办公室. 中国妇幼卫生监测工作手册 (2013版)[M].2013: 208 – 231. http://www.mchscn.org/Article_Show.asp?ArticleID=518.
    [18]
    高伟. 先天性心脏病临床处理时机及方式选择[J]. 中国实用内科杂志, 2013, 33(4): 263 – 267.
    [19]
    Peterson C, Dawson A, Grosse SD, et al. Hospitalizations, costs, and mortality among infants with critical congenital heart disease: how important is timely detection?[J]. Birth Defects Research Part A:Clinical and Molecular Teratology, 2013, 97(10): 664 – 672. doi: 10.1002/bdra.23165
    [20]
    张丽, 相晓妹, 张水平, 等. 西安市空气污染对先天性心脏病影响[J]. 中国公共卫生, 2019, 35(10): 1416 – 1420. doi: 10.11847/zgggws1122077
    [21]
    Ma XJ, Huang GY. Current status of screening, diagnosis, and treatment of neonatal congenital heart disease in China[J]. World Journal of Pediatrics, 2018, 14(4): 313 – 314. doi: 10.1007/s12519-018-0174-2
    [22]
    de-Wahl Granelli A, Wennergren M, Sandberg K, et al. Impact of pulse oximetry screening on the detection of duct dependent congenital heart disease: a Swedish prospective screening study in 39 821 newborns[J]. BMJ, 2009, 338: a3037. doi: 10.1136/bmj.a3037
    [23]
    Coelho R, Teixeira F, Silva AM, et al. Psychosocial adjustment, psychiatric morbidity and quality of life in adolescents and young adults with congenital heart disease[J]. Revista Portuguesa de Cardiologia (English Edition), 2013, 32(9): 657 – 664. doi: 10.1016/j.repce.2013.10.011
    [24]
    Leslie CE, Schofield K, Vannatta K, et al. Perceived health competence predicts anxiety and depressive symptoms after a three-year follow-up among adolescents and adults with congenital heart disease[J]. European Journal of Cardiovascular Nursing, 2020, 19(4): 283 – 290. doi: 10.1177/1474515119885858
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