Severe circumstance of global public health has posed higher requirements for rapid response to public health emergencies in port cities, especially at border ports, and it is urgent to construct a rapid decision-making mechanism for the response to public health emergency in port city in China. In this paper, the basic elements of public health emergency management decision-making, the structure of decision-making system, as well as the experience of port cities in responding to public health emergencies, are summarized. Specific problems in decision-making mechanism for the response to public health emergency in port city were also discussed in the paper, including the risk identification and screening of infectious diseases, novel model for comprehensive risk management of public health event, the application of artificial intelligence technology to construct rapid response infrastructure, and the structure and operation mode of the early-warning decision-making system.
The conronavirus disease 2019 (COVID-19) pandemic exerts a major impact on the world. Understanding the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can help public health personnel to define the prevention and control priorities in practical work. This study summarized the existing literature (update to May 2, 2022) and analyzed and classified the main transmission routes of SARS-CoV-2 based on typical cases and laboratory studies, and proposed relevant prevention and personal protection strategies to provide a basis for more accurate and effective control of SARS-CoV-2 transmission.
The social attributes of people determine that illness is not only a medical problem, but also a social disease. The illness has a wide range of social attributes from its occurrence and development, diagnosis and treatment to its social impacts. The prevention and control of disease require a full participation of the whole society, including the government, medical institutions, social organizations, and individuals. However, a healthy social environment urgently requires further innovations in disease prevention and control concepts and strategies to strengthen social foundations against to various diseases.
Developing simple and sensitive detection methods is of great significance to researches on medical diagnosis, environmental analysis and food safety. As a new biological indicator molecule, aptamers are combined with hybridization chain reaction (HCR) to form a new detection model for sensitive detection of analytes. HCR is a typical amplification technology, which can be carried out without enzyme and self-assembled at room temperature. The aptamer-based HCR technology has be attracted great interest due to its high specificity and sensitivity, simple protocol and low cost. The study reviews basic features of HCR with an emphasis on the application of aptamer-based HCR in detection, such as proteins, enzyme activities, small molecules and tumor cells, etc. Major existing problems of the technology are also discussed. The review is aimed to provide a theoretical reference for establishing a highly efficient and sensitive HCR detection system.