Advance Search
Volume 38 Issue 5
May  2022
Turn off MathJax
Article Contents
ZOU Li-hai, KANG Dian-min. Research progress in carcinogenicity of metalworking fluids[J]. Chinese Journal of Public Health, 2022, 38(5): 634-636. doi: 10.11847/zgggws1135442
Citation: ZOU Li-hai, KANG Dian-min. Research progress in carcinogenicity of metalworking fluids[J]. Chinese Journal of Public Health, 2022, 38(5): 634-636. doi: 10.11847/zgggws1135442

Research progress in carcinogenicity of metalworking fluids

doi: 10.11847/zgggws1135442
  • Received Date: 2021-05-13
    Available Online: 2022-04-29
  • Publish Date: 2022-05-20
  • Metalworking fluids (MWFs) is used in the machinery manufacturing industry in huge quantities and with a large number of exposed workers. MWFs can simply be divided into 2 categories: oil-based and water-based fluids, or by its nature into 4 categories: straight oils, soluble oils, synthetic fluids and semi-synthetic fluids. During machining and grinding operations, MWFs is sprayed directly onto the exposed skin of the operator′s hands or face, or is dispersed into the air of the workplace environment and inhaled by the operator, resulting in occupational health hazards due to mechanical splashing, rotating workpiece forces, atomisation and evaporation, burning or pyrolysis due to increased surface temperature of the metal cutting workpiece. The health hazards of MWFs to skin and respiratory system are well established, but the issue of its carcinogenicity is still debated. In this study, the carcinogenicity of MWFs is reviewed in terms of the relationship between exposure to MWFs and cancer, the relationship between MWFs types and cancer, and the carcinogenic factors of MWFs for providing a reference for further research on the health hazards of MWFs.
  • loading
  • [1]
    刘镇昌. 金属切削液: 选择、配制与使用[M]. 北京: 化学工业出版社, 2007.
    [2]
    Byers JP. 金属加工液[M]. 傅树琴, 译. 北京: 化学工业出版社, 2011.
    [3]
    Eisen EA, Tolbert PE, Monson RR, et al. Mortality studies of machining fluid exposure in the automobile industry I: a standard-ized mortality ratio analysis[J]. American Journal of Industrial Medicine, 1992, 22(6): 809 – 824. doi: 10.1002/ajim.4700220604
    [4]
    Eisen EA, Bardin J, Gore R, et al. Exposure-response models based on extended follow-up of a cohort mortality study in the auto-mobile industry[J]. Scandinavian Journal of Work, Environment and Health, 2001, 27(4): 240 – 249. doi: 10.5271/sjweh.611
    [5]
    Kazerouni N, Thomas TL, Petralia SA, et al. Mortality among workers exposed to cutting oil mist: update of previous reports[J]. American Journal of Industrial Medicine, 2000, 38(4): 410 – 416. doi: 10.1002/1097-0274(200010)38:4<410::AID-AJIM6>3.0.CO;2-5
    [6]
    Friesen MC, Betenia N, Costello S, et al. Metalworking fluid exposure and cancer risk in a retrospective cohort of female autoworkers[J]. Cancer Causes and Control, 2012, 23(7): 1075 – 1082. doi: 10.1007/s10552-012-9976-z
    [7]
    Schroeder JC, Tolbert PE, Eisen EA, et al. Mortality studies of machining fluid exposure in the automobile industry. IV: a case-control study of lung cancer[J]. American Journal of Industrial Medicine, 1997, 31(5): 525 – 533. doi: 10.1002/(SICI)1097-0274(199705)31:5<525::AID-AJIM5>3.0.CO;2-S
    [8]
    Colt JS, Karagas MR, Schwenn M, et al. Occupation and bladder cancer in a population-based case-control study in Northern New England[J]. Occupational and Environmental Medicine, 2011, 68(4): 239 – 249. doi: 10.1136/oem.2009.052571
    [9]
    Costello S, Chen K, Picciotto S, et al. Metalworking fluids and cancer mortality in a US autoworker cohort (1941 – 2015)[J]. Scandinavian Journal of Work, Environment and Health, 2020, 46(5): 525 – 532. doi: 10.5271/sjweh.3898
    [10]
    Savitz DA. Epidemiologic evidence on the carcinogenicity of metalworking fluids[J]. Applied Occupational and Environmental Hygiene, 2003, 18(11): 913 – 920. doi: 10.1080/10473220390237539
    [11]
    Park RM. Risk assessment for metalworking fluids and cancer outcomes[J]. American Journal of Industrial Medicine, 2018, 61(3): 198 – 203. doi: 10.1002/ajim.22809
    [12]
    Zhao YX, Krishnadasan A, Kennedy N, et al. Estimated effects of solvents and mineral oils on cancer incidence and mortality in a cohort of aerospace workers[J]. American Journal of Industrial Medicine, 2005, 48(4): 249 – 258. doi: 10.1002/ajim.20216
    [13]
    Costello S, Friesen MC, Christiani DC, et al. Metalworking fluids and malignant melanoma in autoworkers[J]. Epidemiology, 2011, 22(1): 90 – 97. doi: 10.1097/EDE.0b013e3181fce4b8
    [14]
    Eisen EA, Tolbert PE, Hallock MF, et al. Mortality studies of machining fluid exposure in the automobile industry III: a case-control study of larynx cancer[J]. American Journal of Industrial Medicine, 1994, 26(2): 185 – 202. doi: 10.1002/ajim.4700260205
    [15]
    Betenia N, Costello S, Eisen EA. Risk of cervical cancer among female autoworkers exposed to metalworking fluids[J]. Scan-dinavian Journal of Work, Environment and Health, 2012, 38(1): 78 – 83. doi: 10.5271/sjweh.3193
    [16]
    Friesen MC, Costello S, Eisen EA. Quantitative exposure to metalworking fluids and bladder cancer incidence in a cohort of autoworkers[J]. American Journal of Epidemiology, 2009, 169(12): 1471 – 1478. doi: 10.1093/aje/kwp073
    [17]
    Colin R, Grzebyk M, Wild P, et al. Bladder cancer and occupa-tional exposure to metalworking fluid mist: a countermatched case-control study in French steel-producing factories[J]. Occupational and Environmental Medicine, 2018, 75(5): 328 – 336. doi: 10.1136/oemed-2017-104666
    [18]
    Colt JS, Friesen MC, Stewart PA, et al. A case-control study of occupational exposure to metalworking fluids and bladder cancer risk among men[J]. Occupational and Environmental Medicine, 2014, 71(10): 667 – 674. doi: 10.1136/oemed-2013-102056
    [19]
    Garcia E, Bradshaw PT, Eisen EA. Breast cancer incidence and exposure to metalworking fluid in a cohort of female autoworkers[J]. American Journal of Epidemiology, 2018, 187(3): 539 – 547. doi: 10.1093/aje/kwx264
    [20]
    Garcia E, Picciotto S, Neophytou AM, et al. Lung cancer mortality and exposure to synthetic metalworking fluid and biocides: controll-ing for the healthy worker survivor effect[J]. Occupational and Environmental Medicine, 2018, 75(10): 730 – 735. doi: 10.1136/oemed-2017-104812
    [21]
    Mirer FE. New evidence on the health hazards and control of metalworking fluids since completion of the OSHA advisory committee report[J]. American Journal of Industrial Medicine, 2010, 53(8): 792 – 801.
    [22]
    Järvholm B, Lillienberg L, Sällsten G, et al. Cancer morbidity among men exposed to oil mist in the metal industry[J]. Journal of Occupational Medicine: Official Publication of the Industrial Medical, 1981, 23(5): 333 – 337.
    [23]
    Mirer F. Updated epidemiology of workers exposed to metal-working fluids provides sufficient evidence for carcinogenicity[J]. Applied Occupational and Environmental Hygiene, 2003, 18(11): 902 – 912. doi: 10.1080/10473220390237511
    [24]
    杨立新, 刘印平, 王丽英, 等. 短链氯化石蜡毒性效应及检测技术研究进展[J]. 食品安全质量检测学报, 2015, 6(10): 3795 – 3803.
    [25]
    Suuronen K, Henriks-Eckerman ML, Riala R, et al. Respiratory exposure to components of water-miscible metalworking fluids[J]. The Annals of Occupational Hygiene, 2008, 52(7): 607 – 614.
    [26]
    Woskie SR, Virji MA, Hallock M, et al. Summary of the findings from the exposure assessments for metalworking fluid mortality and morbidity studies[J]. Applied Occupational and Environmental Hygiene, 2003, 18(11): 855 – 864. doi: 10.1080/10473220390237377
    [27]
    Henriks-Eckerman ML, Suuronen K, Jolanki R, et al. Determi-nation of occupational exposure to alkanolamines in metal-working fluids[J]. The Annals of Occupational Hygiene, 2007, 51(2): 153 – 160.
    [28]
    Lijinsky W. The formation and occurrence of polynuclear aromatic hydrocarbons associated with food[J]. Mutation Research, 1991, 259(3/4): 251 – 261.
    [29]
    Apostoli P, Crippa M, Fracasso ME, et al. Increases in polycyclic aromatic hydrocarbon content and mutagenicity in a cutting fluid as a consequence of its use[J]. International Archives of Occupational and Environmental Health, 1993, 64(7): 473 – 477. doi: 10.1007/BF00381094
    [30]
    Chen MR, Tsai PJ, Wang YF. Assessing inhalatory and dermal exposures and their resultant health-risks for workers exposed to polycyclic aromatic hydrocarbons (PAHs) contained in oil mists in a fastener manufacturing industry[J]. Environment International, 2008, 34(7): 971 – 975. doi: 10.1016/j.envint.2008.02.008
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索
    Article views (68) PDF downloads(12) Cited by()
    Proportional views

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return