Study on Relationship Between the Change of Erythrocyte Immune State and the Levels of SOD and LPO in Smoking Adult Man

Objective To examine the relationship between the change of erythrocyte immune state and the leves of SOD and LPO in smoking people.Methods One hundred and fifty-eight healthy adult men were divided into two groups:smoking group (116 cases)and non-smoking control group(42 cases).Plasma red blood cell C3B receptor(RBC-C3bRR),red cell blood immune complex resette(RBC-ICR),superoxide dismutase(SOD)and lipid peroxide(LPO)were determined in the two groups.Results RBC-C3bRR and SOD in the smoking group were markedly lower compared with those of the non-smoking group(P<0.01,P <0.05),while RBC-ICR and LPO were significantly increased (P<0.01).Furthermore,the correlation analysis showed that there was a significantly negatively correlation between SOD and the smoking quantity(r=-0.0584,P<0.05),which is a signifcantly positive correlation between serum LPO and the smoking quantity(r=0.828,P<0.01).In addition,the RBC-C3bRR was related positively to SOD(r=0.785,P<0.01),but negatively to LPO(r=-0.913,P<0.01).Conclusion Erthrocyte immune in smoking people is decreased,which is in relation to the decrease of erythrocyte SOD and the increase of LPO.