Study on Aatagonizing Mutagenesis to B(a)P of Chinese Herbal Medicine and Green Tea

Objective To discuss antagonizing mutagenesis to B(a)P of Chinese herbal medicine and green tea.Methods The Ames test was used in this study to investigate the antimutagenicity of water extract of Chinese herbal medicine and green tea to benzoapyrene B(a)P.Results Except the lowest dosage group,all the other dosage groups of green tea,tea polyphenol,scutellaria barbale,Hedyotis diffusa wildi,xihuangwan,inhibited the reverse mutation of TA98 and TA100 induced by B(a)P significantly (P<0.01).Conclusion Chinese herbal medicine and green tea have the effects of antagonizing mutagenesis to B(a)P.