Effect of taurine on retinal ultrastructure of rats with early-stage diabetic retina

  Objective   To observe retinopathy of diabetic rats, and to investigate the effect of taurine on ultrastructure of ratsith early-stage diabetic retinopathy.

  Methods   50 SD rats were chosen and divided at random into normal group (CON), one-month diabetic group(DM1), one-month taurine-treated diabetic group(DM1+T), three-month diabetic group (DM3), three-month taurine-treated diabetic group. Diabetic rat was induced by injected streptozocin into abdominal cavity once. Diabetic rats were treatedith taurine that were mixedith the food. The ratsere sacrificed at the time of one month, three months after the model being created. Retinal tissues of ratsere observedith optical microscope and transmission electronic micoscope.

  Results   Taurine can effectively protect retinal capillaries and improve optical receptor functions.