Objective To study the influence of phthalic acid esteron drosophilas life span and mutagenesis to drosophi las germ cell.
Methods In drosophilas life span test and SLRL flies were fed with din butylphthalate(DBP)and dinoctyl phthalate(DOP)of identical concentration.
Results Above concentration of 0.02% group flies life span became obviously shor ter compared with the control group; mutation rate of flies in 600, 1.800 mg/L group remar kably differed from that of the control group.
Conclusion DBP and DOP inter fered flies natural development and metabolism, shortened flies life span obviously; DBP and DOP also had mutagenic effect on Droso philas ge m cell.