Effect of nucleic acid on activity of antioxidative enzyme in rats

  Objective   To observe the effect of dietary nucleic acid on antiox idation.

  Methods   Thirty two Wistar rats were divided randomly into three groups(one control group and two experiment groups).The rats were given dietary nucleic acid.After 5 weeks the activity of superox ide dismutase(SOD), malondialdehyde(MDA)and GSHPx, reduced glutathione(GSH)in serum, liver, kidney were measured respectively.

  Results   Compared with control, the activities of SOD, and GSHPx in dietary nucleic acid group were increased and the concentrations of MDA were decreased significantly(P < 0.05).

  Conclusion   Dieatry nucleic acid can increase antiox idative effect and reduce lipid perox idation.