Investigation on status of toxoplasma infection in pregnant women and its vertical transmission

  Objective   To investigate the relationship and status of toxoplasma(T ox)infection between pregnant women and their fetus.

  Methods   Enzym-linked immunosorbent assay(ELISA)was used to detect circulating antigen(CAg), special antibodies IgM and IgG in the blood of pregnant women and fetal umbilical blood.

  Results   Among the 93 cases, 8 were TOX-CA g positive(8.6%), 10 were TOX-IgM positive(10.8%)and 34 were TOX-IgG positive(36.6%)in pregnant women; the three were TOX-CAg 4(4.3%), TOX-I gM 2(2.2%)and TOX-I gG 14(15.1%)r espectively in newborn infants.The over all prevalence rates of to xoplasmosis among the pregnant women and their newborn infants were 45.2%(42/93)and 19.4%(18/93)respectively.the total proportion of vertical transmission was 42.9%, the IgG was 41.3%, the CAg was 50%.

  Conclusion   Pregnant women are at the high risk of toxoplasma infection, and more than 1/3 fetus will get infection from their mother before they give birth.Ther efore, Sero-epidemiologic survey in pregnant women should be strengthened in better child-bearing.