Objective To investigate the properetiology of Idiopathic Talipes Equinovarus(ITEV)in Liaoning, Jilin and Heilongiang province of China.
Methods 121 proposita data information were obtained by follow-up and questionnaire survey.220 normal person infor mation matched with control group to complete case-control study for some risk factors of ITEV.
Results 9 persons were excluded since they had some other defor mities.After this process.112 proposita were involved.The ratio of ITEV between male and female was 2.6:1, and bilateral deformity was seen in 50% or more of ITEV cases.And in unilater al cases, the right side was more often involved than that of left side.There were more ITEV births in summer/winter than that of spring/autumn.Among all environmental factors, taking medicine before or during pregnancy was significant difference between case and control group(χ2=8.64 and 13.49;P < 0.01).And 65.2% mother had abnormal uterus factors in case group, which had significant difference compared with control group(χ2=49.29, P < 0.01).There was no difference in maternal smo king, drinking and having disease during pregnancy between case and control group(P > 0.05).
Conclusion Taking medicine before or during pregnancy and abnormal uterus factors may play important roles in etiology of ITEV.