Study on immunity system cute damage in mice exposed to BPA

  Objective   To study the effects of bisphenol A(BPA)on the immune system in mice.

  Methods   The mice were given BPA of different dosages through mouth for 7 days.And their index of organs, the phago cytotic rate of macrophage in the belly cavity, the hemolysis plaqu-eforming ability, and the thickness of feet were measured.

  Results   The phagocytosis, the plaque-for ming number and delayed type hypersensitivity in middle, hig h groups were inhibited, while those all were reinforced in low group.

  Conclusion   BPA has two phases influence on the immune system of the mice meanwhile low dosage BPA can reinforce the humoral and cellular immunity, and higher dosage can inhibit it.