Study on human papilloma virus infection association with cervical erosion among female congential tract

Objective To explore the genotype and distribution of humam papilloma viruses among cervical erosion patients,and to guide the preventing and treat ing cancer of uterine cervix.Methods T he cervical erosion specimens were collected and divided into two groups,the CA group and no-CA group.The immunohistochemistry assay and PCR technique were used to detect the genotypes of HPV-DNA.Results The 76 cases(67.8%)in CA g roup and the 163 cases(47.7%) in no-CA group were confirmed to be HPV-DNA positive.T he positive rates of HPV were Ⅰ° 55.5%,Ⅱ° 64.7% and Ⅲ° 83.3% in CA group;and Ⅰ° 32.8%,Ⅱ° 49.6% and Ⅲ° 62.3% in non-CA group among cervical erosion patients respectively.The genotype of HPV-DNA was 6,11,16,18,58,45 and 33.Conclusion T here is hig her incidence of HPV among cerv ical erosion pat ients in the region,and the incidence of HPV has a positive association ith the cervical erosion deg rees.It is of paramount importance to control HPV infection and treat cervical erosion effectively for preventing and treating cancer of uterine cervix.