Study on protective effects of soybean compound on radiation from gamma rays

Objective To study the radiation-protective effects of soybean compound in radiated mice from gamma rays.Methods Three batches normal male Kunming mice,every batch of mice was evenly randomized into five groups according to body weight:normal control group,radiated control group and two intervention groups.In the course of experimentation,two intervention groups were given different doses of soybean complex for 30 day.First experiment:the whole body of mice besides normal control group was subjected to 3.0 Gyγ-radiation once.The WBC was observed on the 3th,14th day after radiation.Second experiment:the whole body of mice except normal control group was subjected to 5.0 Gyγ-radiation once.The granulocytes and the micronucleated polychromatic erythrocytes in bone-marrow were observed on the 3th day after radiation.Third experiment:the whole body of mice except normal control group was subjected to 7.0 Gyγ-radiation once.The SOD activity and the MDA content of blood and liver tissue in mice were observed on the 7th day after radiation.Results Compared with radiated control group,the WBC of high and low doses of soybean complex groups was respectively increased on the 3th day and the 14th day after radiation(P<0.05).And in two intervention groups,the granulocytes in bone-marrow increased significantly(P<0.05)and the micronucleated polychromatic erythrocytes in bone-marrow decreased significantly(P<0.05)after radiation.In addition,the SOD activity of blood and liver tissue increased significantly(P<0.05),and as well as the MDA content of blood decreased compared with radiated control groups.(P<0.05).Conclusion Soybean compound could prevent the WBC in distal blood and the granulocytes in bone-marrow decreased after radiation,restrained the production of the micronucleated polychromatic erythrocytes,increased the antioxidant ability of radiated mice,and released the irradiation injury fromγ-rays.