Inhibition of high effect cypermethrin on Na-K-ATP_ase of blattella germanica

  Objective   To undestand the operational mechanisms of high effect cypermethrin and to provide theoretical basis and useful methods by researching the dosage effect and the time effect between high effect cypermethrin and Na-K-ATP_ase activities of Blattella germanica.

  Methods   Quantitative high effect cypermethr in of different concentration was sprayed according to the method of GB 13917.1-13917.8-92 for insecticide registered testing indoor effect.The activities of Na-K-ATP_ase were determined by using ATP_ase Kit.

  Results   Inhibition of high effect cypermethr in on Na-K-ATP_ase activities of Blattella germanica showed concentration gradient effect in 48 hours.The correlation of concentration of high effect cypermethrin and inhibiting time effect on Na-K-ATP_ase activities of Blattella germanica in 144 hours and death rate of Blattella germanica in 72 hours was positive relationship.

  Conclusion   Na-K-ATP_ase is one of the targets of high effect cypermethrin.Because of sensitivity decrease of Na-K-ATP_ase, tar get resistance may be one of the important resistant mechanisms to high effect cypermethrin.