Effect of lycopene on antioxidative enzyme in rats induced by Cd

  Objective   To observe the effect of Lycopene(LP)on antioxidation in rats induced by Cd.

  Methods   The rats were given Cd and LP.After 4 weeks the activity of SOD, MDA and GSH-Px, GSH, CAT in serum and liver were measured respectively.

  Results   The activities of antioxidative enzymes in model group were reduced.Compared with model group, the activities of SOD and GSH-Px in LP group were increased and the concentrations of MDA were decreased significantly(P < 0.05).

  Conclusion   LP could increase antioxidative effect and reduce lipid peroxidation in Wistar rats induced by Cd.