Study on change of blood and cytogenetics after abdominal irradiation

  Objective   To study the change of blood and cytogenetics of the cancer patients after radiotherapy.

  Methods   46 patients who suffered from the abdominal tumor were radiated by the accelerating machine singly or the combination of γ irradiation and accelerating machine, five days a week and once aday.The dose in the center of the tissue was 2 Gy, and the total dose was 43-60 Gy.After irradiation the counts of leukocyte and lymphocyte, and the rates of micronuclear and chromosome aberration of lymphocyte were observed.

  Results   The counts of leukocyte and lymphocytle were reduced obviously after radiotherapy.Moreover, the rates of micronuclear and chromosome aberration were increased markedly.

  Conclusion   The haemocyte change of the cancer patients was similar to acute irradiation of whole body, but the degree was lightened obviously and the speed became slow.The distribution of chromosome aberration was deviated from Poisson's distribution.