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SUN Ying, LU Xiao-bo, HUANG Xiu-shuang, . Study of lipid peroxidation on brain of rat offspring exposed to lead[J]. Chinese Journal of Public Health, 2004, 20(2): 200-201.
Citation: SUN Ying, LU Xiao-bo, HUANG Xiu-shuang, . Study of lipid peroxidation on brain of rat offspring exposed to lead[J]. Chinese Journal of Public Health, 2004, 20(2): 200-201.

Study of lipid peroxidation on brain of rat offspring exposed to lead

  •   Objective   To study the lipid perox idation on developmental central nervous system.
      Methods   LPO level, the GSH content, and the activity of SOD, CAT, GSH-PX in the brain of rat offsprings exposed to lead during pregnant and breast-feed period were determined.
      Results   The LPO level in middle and high lead-exposed groups increased and the SOD activity decreased compared with the control, the activity of CAT in high lead-exposed group decreased.
      Conclusion   Lead ex erted developmental neurotoxicity through lipid peroxidation.
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