Inflnuence of laminaria japonica polysaccharides on blood gas of hypoxic mice and its anti-fatigue effect

  Objective   To study the effect of Laminaria Japonica Polysaccharides(LJP)on the blood gas of hypoxic mice and its anti-fatigue effect.

  Methods   Different doses of LJP10, 20, 50, 100 mg/(kg·d)was poured into the stomaches of the experimental mice for 10 days continously and then the fatigue experiment and the hermetic hypoxia experiment were carried out.

  Results   LJP can significantly lengthen the burden swimming time and the survival time, which was under the condition of hypoxia and normal atmospheric pressure, in experimental mice.Additionally, LJP can raise the quantity of hemoglobin in the experimental mice and cause the dissociation of oxyhemoglobin to promote the release of oxygen.

  Conclusion   LJP can raise the oxygen utilizing ability of the experimental mice and enhance the hypoxia tolerant capacity as well as the anti-fatigue capacity of the experimental mice.