Objective To investigate the prevalent status of HIV-1 subtype C epidemic among different populations in Shandong province.
Methods DNA fragments of HIV-1 env gene were amplified by nested PCR from persons infected with HIV-1.C2-V3 and adjacent region were sequenced.
Results These 7 cases were confirmed to be infected with HIV-1 subetype C strain, 5 strains are nearer to 07-BC, and 2 strains are nearer to 08-BC in phylogenetic tree.
Conclusion There may be CRFs of HIV-1 C strain in Shandong, C subtype distributed in 4 kinds of populations and had 3 various routes to transmit.