Objective To study the protective effect of β-carotene on injury of alveolar macrophage of rats induced by cooking oil fume.
Methods Rats were exposed to cooking oil fume and treated with β-carotene at the same time. After treatment, memberane fluidity and content of LPO were detected in different times.
Results Cooking oil fume could cause lipid peroxide of lung in rats and reduce membrane fluidity of alveolar macro phage. While β-carotene could lead to increase of memberane fluidity and decrease the content of LPO significantly.
Conclusion β-carotene played certain protective role in lipid peroxide of lung and injuries of alveolar macrophage induced by cooking oil fume in rats.