Research of diagnosis and therapy effect of praziquantel on suspected cerebral cysticercosis

  Objective   To observe the diagnosis and therapy effect of praziquantel(PQT)on suspected cerebral cysticercosis.

  Methods   To apply diagnosis therapy on suspected cerebral cysticercosis with large dose PQT(50mg/kg/d, 12d).

  Results   Thirtyeight cases were confirmed cerebral cysticercosis in 93 cases of suspected cerebral cysticercosis, 42 cases were basical diagnosed other central nervous system diseases, 13 cases were still unconfirmed.27 of 38 cases of cerebral cysticercosis showed obvious insecticide effect, 17 cases of which counterchecked CT or MRI showed the foci shrinked and surrounding edema obsorbed or disappeared, 2 cases showed the foci manifold and had cyst appearance.Other 11 cases of cerebral cysticercosis did not show obvious insecticide effect, they were diagnosed by CT or MRI appearance of focus shrinked or disappeared.The clinical symptom of 38 cases of cerebral cysticercosis disappeared after 1 or 2 period of anti-cysticercosis treatment, 31 cases of which countercheck CT or MRI showed the foci absorbed absolutely, 5 cases had calcify appearance.

  Conclusion   Large dose of PQT had preferable diagnosis and treating effect on suspected cerebral cysticercosis.