Determination of adduct actions of mixed pesticides on DNA by ultraviolet spectral method

  Objective   To study the adduct actions of mixed pesticides on DNA.

  Methods   To study the adduct reactions of pestiside on DNA by ultraviolet spectral analysis.

  Results   The change of ultraviolet spectrum of DNA would be caused by single or mixed Malathion、Carbonfuran、Cypermethrin.

  Conclusion   Single or mixed Malathion、Carbonfuran and Cypermethrin may adduct with DNA after they enter body.If these DNA adducts are not repaired or misrepaired before cell duplication, the gene mutation and chemical damage would happen.