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黑龙江省男男性行为者HIV暴露后预防使用情况及影响因素分析

Awareness and willingness to use post-exposure prophylaxis and influencing factors among men who have sex with men in Heilongjiang province: a cross-sectional survey

  • 摘要:
    目的 对黑龙江省男男性行为者(MSM)HIV暴露后预防服务利用情况进行调查,了解该人群艾滋病暴露后预防服务(PEP)的接受意愿及影响因素,为进一步在全省推广暴露后预防工作和制定实施方案提供可靠数据支持。
    方法 于2022年9—11月采用滚雪球法招募年龄≥18周岁、HIV阴性或自身不清楚HIV感染情况的MSM为调查对象,收集社会人口学特征、艾滋病知识知晓率及相关行为、PEP接受意愿及其可能的影响因素等。采用χ2检验对MSM的PEP影响因素进行单因素和多因素非条件logistic回归分析。
    结果 共调查404人,68.812%的人在HIV暴露后愿意使用PEP服务。单因素分析发现,婚姻状况、文化程度、月收入、性取向、最主要寻找男伴的场所、HIV知识知晓、肛交时性角色、最近6个月同性性伴数量、最近6个月与同性肛交安全套使用频率、HIV检测次数、PEP知晓情况、可承担PEP最高价格对PEP接受意愿差异均有统计学意义(P<0.050)。多因素非条件logistic 回归分析显示,文化程度(OR=5.500,95%CI=2.174~13.911)、同性性伴数量(OR=21.708,95%CI=6.258~75.305)、最近6个月与同性肛交安全套使用频率(OR=9.301,95%CI=2.711~31.904)、HIV检测次数(OR=3.218,95%CI=1.500~6.904)为PEP服务的主要影响因素。
    结论 黑龙江省男男性行为者对PEP服务接受意愿较高。PEP作为一项有效的药物干预措施应尽快在全省推广,促进MSM主动就医,减少HIV感染。

     

    Abstract:
    Objective To assess the awareness and willingness to use post-exposure prophylaxis (PEP) and influencing factors among men who have sex with men (MSM) in Heilongjiang province for further promotion and implementation of PEP programs among MSM.
    Methods Using snowball sampling, we recruited 404 MSM residing in Harbin city who were ≥18 years old, HIV negative, or unaware of their HIV status. Face-to-face interviews were conducted among the MSM from September to November 2021 to collect relevant information by taking a self-developed PEP questionnaire based on that used in the national sentinel surveillance program. Chi-squared tests, univariate and multivariate unconditional logistic regression analyses were used to analyze factors influencing MSM's willingness to accept PEP.
    Results Of the MSM surveyed with a median age of 36 years, 68.812% reported the willingness to use PEP. Univariate analysis revealed that marital status, education, personal monthly income, sexual orientation, primary venue for finding male partners, HIV knowledge, sexual role during anal intercourse, number of male sex partners in the least 6 months, frequency of condom use during anal sex with men in the least 6 months, number of HIV tests, PEP awareness, and the maximum acceptable price of PEP were significant factors associating with willingness to accept PEP (all P<0.050). Multivariate unconditional logistic regression analysis showed that education level (odds ratio OR=5.500, 95% confidence interval 95%CI: 2.174–13.911), number of male sex partners (OR=21.708, 95%CI: 6.258–75.305), frequency of condom use during anal sex with men in the least 6 months (OR=9.301, 95%CI: 2.711–31.904), and number of HIV tests (OR=3.218, 95%CI: 1.500–6.904) were the main factors influencing willingness to use PEP.
    Conclusions The willingness to accept PEP is relatively high among MSM in Heilongjiang province, suggesting that PEP should be promoted among local MSM to reduce HIV infection.

     

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