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河北省成年居民血脂异常患病情况及其影响因素分析

Prevalence of dyslipidemia and its influencing factors among adult residents in Hebei province: a cross-sectional survey

  • 摘要:
    目的 了解河北省成年居民血脂异常患病情况及其影响因素,为该地区居民的血脂异常防治工作提供参考依据。
    方法 于2020年9月 — 2021年6月采用多阶段随机抽样方法在河北省石家庄晋州市、保定莲池区、沧州新华区、承德双滦区、廊坊大城县、邯郸邯山区、邢台内丘县、衡水故城县、唐山玉田县和定州市10个县(区)抽取12187名 ≥ 18岁常住居民进行问卷调查、体格检查和实验室检测,分析河北省成年居民血脂异常的患病情况,并应用多因素非条件logistic回归模型分析该地区成年居民血脂异常患病的主要影响因素。
    结果 河北省成年居民血脂异常患病率为32.8%(4000/12187),高总胆固醇(TC)血症、高甘油三酯(TG)血症、高低密度脂蛋白胆固醇(LDL-C)血症和低高密度脂蛋白胆固醇(HDL-C)血症的患病率分别为5.4%(662/12187)、14.0%(1701/12187)、4.8%(582/12187)和15.5%(1886/12187)。多因素非条件logistic回归分析结果显示,年龄 ≥ 25岁、现在吸烟、超重、肥胖、中心性肥胖、体脂百分比 ≥ 27.2%和基础代谢率 ≥ 1 504 kcal是河北省成年居民血脂异常患病的危险因素,女性、居住在农村和静态行为时间2~4 h/d是河北省成年居民血脂异常患病的保护因素;年龄 ≥ 25岁、文化程度大专及以上、现在吸烟、中心性肥胖和体脂百分比 ≥ 37.9%是河北省成年居民高TC血症患病的危险因素,基础代谢率1199~1 503 kcal是河北省成年居民高TC血症患病的保护因素;年龄25~64岁、现在吸烟、畜禽肉摄入量300~500克/周、超重、肥胖、中心性肥胖和体脂百分比 ≥ 27.2%是河北省成年居民高TG血症患病的危险因素,女性是河北省成年居民高TG血症患病的保护因素;年龄 ≥ 25岁、中心性肥胖、静态行为时间 ≥ 2 h/d和体脂百分比 ≥ 37.9%是河北省成年居民高LDL-C血症患病的危险因素,基础代谢率1199~1 503 kcal是河北省成年居民高LDL-C血症患病的保护因素;少数民族、现在吸烟、超重、肥胖、中心性肥胖、身体活动不足、体脂百分比33.0%~37.8%、基础代谢率 ≥ 1 327 kcal是河北省成年居民低HDL-C血症患病的危险因素,女性、45~54岁、居住在农村、饮酒、畜禽肉摄入量 > 500克/周和静态行为时间 ≥ 2 h/d 是河北省成年居民低HDL-C血症患病的保护因素。
    结论 河北省成年居民血脂异常患病率相对较低,性别、年龄、居住地、是否现在吸烟、体质指数、是否中心性肥胖、静态行为时间、体脂百分比和基础代谢率是该地区成年居民血脂异常患病的主要影响因素。

     

    Abstract:
    Objective To investigate the prevalence of dyslipidemia and its influencing factors among adults in Hebei province, to provide a reference for the prevention and control of dyslipidemia in the population.
    Methods From September 2020 to June 2021, 12 187 permanent residents aged ≥ 18 years were recruited from 60 rural villages/urban communities in 10 counties/districts of Hebei province using a stratified multistage random sampling method and underwent in-person questionnaire interview, physical examination, and laboratory tests. The prevalence of dyslipidemia and its components was analyzed, and an unconditional multivariate logistic regression model was used to analyze the main factors influencing dyslipidemia and its components in the participants.
    Results  Among all the participants, the prevalence of dyslipidemia was 32.8% and the prevalence rates of hypercholesterolemia, hypertriglyceridemia, hyper-low-density lipoprotein cholesterolemia (LDL-C), and hypo-high-density lipoprotein cholesterolemia (HDL-C) were 5.4%, 14.0%, 4.8%, and 15.5%, respectively. Unconditional multivariate logistic regression analysis showed that among adult residents, age ≥ 25 years, current smoking, overweight, obesity, central obesity, body fat percentage ≥ 27.2%, and basal metabolic rate ≥ 1 504 kcal were risk factors for dyslipidemia, whereas female gender, rural residence, and sedentary time of 2 – 4 hours per day were protective factors against dyslipidemia; age ≥ 25 years, college education or higher, current smoking, central obesity, and body fat percentage ≥ 37.9% were risk factors for hypercholesterolemia, whereas a basal metabolic rate of 1 199 – 1 503 kcal was a protective factor; age 25 – 64 years, current smoking, consumption of animal and poultry meat 300 – 500 g per week, overweight, obesity, central obesity, and body fat percentage ≥ 27.2% were risk factors, whereas female gender was a protective factor for hypertriglyceridemia; age ≥ 25 years, central obesity, sedentary time ≥ 2 hours per day, and body fat percentage ≥ 37.9% were risk factors, whereas basal metabolic rate 1 199 – 1 503 kcal was a protective factor for hyper-LDL-C; ethnic minority, current smoking, overweight, obesity, central obesity, physical inactivity, body fat percentage 33.0% – 37.8%, and basal metabolic rate ≥ 1 327 kcal were risk factors, whereas being female, aged 45 – 54 years, living in rural areas, drinking alcohol, consuming livestock and poultry meat > 500 g per week, and being sedentary for ≥ 2 hours per day were protective factors for hypo-HDL-C.
    Conclusions The prevalence of dyslipidemia in adults in Hebei province is relatively low. Sex, age, place of residence, current smoking, body mass index, central obesity, sedentary behavior time, body fat percentage, and basal metabolic rate are the main influencing factors of dyslipidemia in adults in this region.

     

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