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河北省≥40岁居民慢性阻塞性肺疾病患病情况及其影响因素分析

Prevalence and determinants of chronic obstructive pulmonary disease among residents aged 40 years and older in Hebei province: a cross-sectional survey

  • 摘要:
    目的 了解河北省≥40岁居民慢性阻塞性肺疾病(慢阻肺)患病情况及其影响因素,为制定当地的慢阻肺防控措施提供参考依据。
    方法 于2019年7月—2020年5月采用多阶段随机抽样方法在河北省保定市定州市、衡水市冀州区、保定市莲池区、廊坊市香河县、保定市雄县、张家口市万全区、承德市双桥区、唐山市滦州市、沧州市新华区、邯郸市鸡泽县和邢台市内丘县11个县区监测点抽取6 600名≥40岁常住居民进行问卷调查、身体测量和肺功能检查,经复杂加权调整后估算慢阻肺的患病率,并应用survey logistic多因素回归模型分析该地区≥40岁居民患病的主要影响因素。
    结果 河北省最终纳入分析的6 228名≥40岁居民中,患慢阻肺者565例,经复杂加权后慢阻肺患病率为9.10%;survey logistic多因素回归分析结果显示,年龄≥50岁、现在吸烟、既往吸烟、有呼吸系统疾病史、有呼吸系统疾病家族史和有慢性呼吸道症状是河北省≥40岁居民慢阻肺患病的危险因素,女性、少数民族、冀中和冀南地区是河北省≥40岁居民慢阻肺患病的保护因素。
    结论 河北省≥40岁居民慢阻肺患病率较低,性别、年龄、民族、地区、吸烟情况、有无呼吸系统疾病史、有无呼吸系统疾病家族史和有无慢性呼吸道症状是当地居民慢阻肺患病的主要影响因素。

     

    Abstract:
    Objective To investigate the prevalence of chronic obstructive pulmonary disease (COPD) and its influencing factors among residents aged 40 years and older in Hebei province, and to provide a reference for the development of local COPD prevention and control strategies.
    Methods Study participants were 6 600 permanent residents aged 40 years and older recruited from urban/rural communities of 11 county-level COPD surveillance sites (counties/districts) in Hebei province using multistage random sampling. Face-to-face interviews with a standardized questionnaire developed by the Chinese Center for Disease Control and Prevention, physical examinations, and pulmonary function tests were conducted among the participants from July 2019 to May 2020. The prevalence of COPD was estimated using complex weighting adjustments, and a multivariate unconditional logistic regression model was used to analyze the main factors influencing COPD among the participants.
    Results Of the 6 228 participants finally included in the analysis, 565 cases of COPD were identified. After complex weighting, the prevalence of COPD was 9.10%. Multivariate survey logistic regression analysis showed that age ≥50 years, current smoking, previous smoking history, history of respiratory diseases, family history of respiratory diseases, and chronic respiratory symptoms were risk factors for COPD in the participants; while, female gender, ethnic minority, and residence in central and southern Hebei province were protective factors against COPD.
    Conclusions  The prevalence of COPD among residents aged 40 years and older in Hebei province is relatively low. Gender, age, ethnicity, geographic region, smoking status, history of respiratory diseases, family history of respiratory diseases, and chronic respiratory symptoms are the main influencing factors of COPD among residents of the province.

     

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