Abstract: Premenstrual syndrome (PMS) is a common affective disorder among women of reproductive age, typically associated with the menstrual cycle, and significantly impacts women's learning, work, and daily life. Exercise can stimulate the release of various neurotransmitters and hormones in the brain. These substances, often referred to as "happy hormones", play a crucial role in mood regulation, helping to alleviate stress and anxiety, and reduce feelings of depression and dejection. In recent years, research on exercise interventions to improve negative mood in women with PMS has gained significant attention. This review aims to investigate the effectiveness of different exercise modalities on negative mood in women with PMS and to summarize existing exercise interventions to provide theoretical guidance for promoting health in women with PMS through exercise.