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因果机器学习的原理、方法及其在疾病防治的创新应用

Definition, methods, and applications of causal machine learning in medicine

  • 摘要: 随着医疗科学技术的快速演进,机器学习作为关键要素已深度融入精准医疗。但传统机器学习方法往往聚焦于自变量与结局变量之间的相关性分析,难以精准识别因果关系,易导致临床结论偏差,影响临床决策的准确性与可靠性。因果机器学习能有效突破这一瓶颈,其在医学领域的应用范围正逐步扩大。本文系统地阐述了因果机器学习的定义与相关概念,明确了其在疾病防治中的具体适用范围,并深入剖析了其相较于传统机器学习、传统统计模型和因果推断的独特优势。进一步详细阐述了因果机器学习在医学实践中的具体方法流程、操作步骤以及关键技术要点。最后,结合具体的案例讲解因果机器学习在疾病干预措施中的应用及其优缺点,旨在规范并促进其在医学领域的广泛应用。

     

    Abstract: With therapid advancement of medical science and technology, machine learning has become an integral component of precision medicine. However, traditional machine learning methods often focus on the correlation analysis between independent and outcome variables, which can hinder their ability to accurately identify causal relationships. This limitation leads to biased clinical conclusions, impacting the precision and reliability of clinical decision-making. Causal machine learning has emerged as a promising approach to overcome these limitations, and its application in the medical field is expanding. This paper systematically explores the definition and core concepts of causal machine learning, clarifies its specific application scope in disease prevention, and delves into its unique advantages over traditional machine learning, statistical models, and causal inference. Furthermore, it outlines the practical methodologies, operational steps, and key technical aspects of causal machine learning in medical practice. By presenting specific case studies, the paper discusses the applications of causal machine learning in disease prevention, highlighting both its strengths and weaknesses. Ultimately, the goal is to standardize and promote the scientific application of causal machine learning in the medical domain.

     

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