高级检索

我国成年人膳食炎症指数与高血糖关联：基于中国健康与营养调查数据分析

Association between dietary inflammatory index and hyperglycemia among adults in China: an analysis of the CHNS database

    摘要
  • 摘要:
    目的 探讨我国成年人能量调整膳食炎症指数（E-DII）与高血糖患病风险及空腹血糖（FPG）水平的关联。
    方法 选取2009年、2015年和2018年“中国健康与营养调查”中9 363名至少参加2轮调查且具有完整膳食调查数据和血糖检测指标的≥18岁成年人作为研究对象，基于定量食物频率问卷（food frequency questionnaire, FFQ）计算E-DII，根据各调查年份E-DII五分位数将研究对象分为5组（Q1～Q5组），分别采用倾向性评分逆概率加权（IPTW）法校正的三水平logistic混合效应模型和三水平线性混合效应模型分析我国成年人E-DII与高血糖患病风险及FPG水平的关联。
    结果 9 363名研究对象基线平均年龄为（51.4±13.1）岁，平均随访5.6年，E-DII得分为−4.5～5.2分，平均值为0.6分，高血糖患病率为24.2%。以E-DII Q5组为参照组，调整相关混杂因素后，全人群E-DII Q2组高血糖患病风险较低（OR=0.616，95%CI=0.470～0.807）；男性、基线45～59岁组、农村居民、城市居民与全人群结果类似。全人群E-DII Q4组FPG水平降低0.046 mmol/L（95%CI= −0.091～−0.001）；女性Q1组FPG水平降低0.120 mmol/L（95%CI= −0.216～−0.024）；基线18～44岁组Q1组和Q4组FPG水平分别降低0.160 mmol/L（95%CI= −0.281～−0.039）和0.128 mmol/L（95%CI= −0.238～−0.018）；城市居民Q3组和Q4组FPG水平分别降低0.195 mmol/L（95%CI= −0.349～−0.041）和0.180 mmol/L（95%CI= −0.330～−0.029）。
    结论 改善促炎膳食对控制我国成年人空腹血糖水平、降低高血糖患病风险可能具有益处。

     

    Abstract:
    Objective To investigate the associations of the energy-adjusted dietary inflammatory index (E-DII) with hyperglycemia risk and fasting plasma glucose (FPG) level among adults in China.
    Methods A total of 9 363 adults aged ≥ 18 years who participated in at least two rounds of the China Health and Nutrition Survey (CHNS) in 2009, 2015, and 2018, with complete dietary data and blood glucose measurements, were included. The E-DII was calculated based on a quantitative food frequency questionnaire (FFQ). Participants were assigned into quintiles (Q1–Q5) according to the E-DII distribution in each survey year. The associations of E-DII with hyperglycemia risk and FPG level were analyzed via a three-level logistic mixed-effects model and a three-level linear mixed-effects model, respectively, with inverse probability of treatment weighting (IPTW) for confounding adjustment.
    Results The baseline mean age of the 9 363 participants was (51.4 ± 13.1) years, with an average follow-up of 5.6 years. The E-DII scores ranged from −4.5 to 5.2, with a mean of 0.6. The prevalence of hyperglycemia was 24.2%. After adjusting for confounders, compared with the Q5 group (highest pro-inflammatory diet), the Q2 group in the overall population had a decreased risk of hyperglycemia (OR = 0.616, 95%CI: 0.470 to 0.807). Similar trends were observed in males, individuals aged 45–59 years at baseline, both rural and urban residents, and the overall population. In the overall population, the Q4 group exhibited a 0.046 mmol/L decrease in FPG (95%CI: −0.091 to −0.001). In females, the Q1 group showed a 0.120 mmol/L reduction in FPG (95%CI: −0.216 to −0.024). Among participants aged 18–44 years at baseline, the Q1 and Q4 groups had FPG reductions of 0.160 mmol/L (95%CI: −0.281 to −0.039) and 0.128 mmol/L (95%CI: −0.238 to −0.018), respectively. Urban residents in the Q3 and Q4 groups demonstrated FPG decreases of 0.195 mmol/L (95%CI: −0.349 to −0.041) and 0.180 mmol/L (95%CI: −0.330 to −0.029), respectively.
    Conclusions Reducing dietary inflammatory potential may aid in FBG control and hyperglycemia prevention among Chinese adults.

     

    • HTML全文
    • 参考文献(41)
    • 相关文章
    • 施引文献
  • 资源附件(0)

/

返回文章
返回