Objective To understand the current status and influencing factors of the first-dose and full-course vaccination for human papillomavirus (HPV) among girls born in Beijing from 2009 to 2015, thus providing evidence for formulating HPV vaccination strategies for girls.

Methods Data related to HPV vaccination for 691 632 girls born between January 1, 2009 and December 31, 2015 and registered in the Beijing Immunization Information System were collected. The current status and influencing factors of the first-dose and full-course vaccination for HPV were analyzed.

Results Among the 691 632 girls born in Beijing from 2009 to 2015, 27 011 girls received the first dose of HPV vaccine, with the first-dose vaccination rate of 3.91%; 12 534 girls received the full course of HPV vaccines, with the full-course vaccination rate of 1.81%. Multivariate unconditional logistic regression analysis results showed that girls born in Beijing between 2010 and 2011, as well as those in areas covered by the HPV vaccination program, had higher first-dose vaccination rates for HPV. In contrast, girls born in Beijing between 2012 and 2015, those with non-local or unknown household registration, and those living in suburban and outer suburban areas had lower first-dose vaccination rates. Among the girls born in Beijing, those residing in areas covered by the HPV vaccination program had a high full-course vaccination rate, while those born between 2011 and 2015, those with unknown household registration, and those living in outer suburban areas had lower full-course vaccination rates.

Conclusions The girls born in Beijing between 2009 and 2015 had lower first-dose and full-course vaccination rates for HPV, especially those born between 2012 and 2015, living in outer suburban areas, and in areas not covered by the HPV vaccination program.