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主动搜索网络直报系统学校传染病聚集性疫情的R语言应用:以广东省为例

Application of R language in active detection of infectious disease clusters in schools within the Notifiable Disease Surveillance and Reporting System: a case study of Guangdong province

  • 摘要:
    目的  编写R语言程序处理传染病网络直报系统中填写格式复杂的“患者工作单位”信息,主动搜索学校聚集性疫情。
    方法 以2024年广东省急性出血性结膜炎、百日咳及其他感染性腹泻病传染病报告卡数据为例,应用R语言4.1.0软件编写主动搜索程序,对“患者工作单位”予以文本分析并整理成规范化学校名称,按学校名称计数,以固定阈值法主动搜索学校聚集性疫情,并与突发公共卫生事件管理信息系统(以下简称“突发网”)报告的疫情进行对比。
    结果  按照突发网报告标准设置搜索阈值时,主动搜索程序的阳性预测值达100.00%;突发网报告的学校聚集性疫情67.65%(23/34)可以被主动搜索程序识别;60.87%(14/23)的聚集性疫情识别时间晚于突发网报告时间,但是39.13%(9/23)的聚集性疫情识别时间已经与突发网报告时间同步;并且额外识别11起应报未报突发网的疫情。当降低搜索阈值时,主动搜索程序可以识别更多可能需要报告突发网的疫情,并且2起聚集性疫情的识别时间可以早于突发网报告时间。
    结论 主动搜索程序可作为突发网的有力补充,为学校传染病疫情的早防早控提供技术支撑。

     

    Abstract:
    Objective To develop an R program for processing complex work unit entries in the Notifiable Disease Surveillance and Reporting System, enabling active searching of school-based cluster epidemics.
    Methods Taking the data of acute hemorrhagic conjunctivitis, pertussis, and other infectious diarrhea diseases in Guangdong province, 2024 as an example, we designed an active searching algorithm in R 4.1.0. The program standardizes unstructured school names via text mining algorithms, counts cases by normalized school name, actively search for school-based cluster epidemics with the fixed threshold method, and compare them with the epidemics reported in the Public Health Emergency Management Information System (PHEMIS).
    Results When being aligned with PHEMIS reporting thresholds, the R program showed the positive predictive value of 100.00%. Among the reported school-based cluster epidemics, 67.65% (23/34) were detected by the R program. The R program identified 60.87% (14/23) cluster epidemics later than PHEMIS but achieved synchronized reporting of 39.13% (9/23) cluster epidemics. Moreover, the R program revealed 11 clusters meeting PHEMIS criteria but not reported. When the thresholds were lowered, more potential cluster epidemics were detected, and 2 signals were earlier than PHEMIS alerts.
    Conclusions This active searching framework can serve as a powerful supplement to PHEMIS, demonstrating operational value for early detection and containment of school-based cluster epidemics.

     

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