Abstract: Objective To explore the effect of comprehensive sanitary and anti-epidemic measures for controlling epidemic of communicable disease and improving health consciousness in residents of ear thquake area.Methods Two investigation were conducted before and after the intervention among 9 644 participants of 3 106 households in 5 villages selected.Results The injured people was 152.The people dead was 59.House destruction rate was 99.84%.95.30% of refugees lived in tent.0.52% of refugees had fever,diarrhea,ophthalmopathy.87.02% of refugees.drinking water was supplied by the government.96.88% of refugees.food was provided by the government.96.36% of refugees received health education.Conclusion There was no communicable disease prevalence among local residents.Comprehensive sanitary and anti-epidemic measures,health education,environment ster ilization,supply of drinking water,reasonable disposal of corpses are effective intervention measures.