Abstract: This article reports that the colour TV radiation affects on genetic, reproductive system and scrum cholesterol concentration in the mouse. After 37 days(3 hours Per day) of colour TV radiation, we couldn't discover any significative change such as the average weight of the female pregaant mouse; the rate of being pregnancy; the average weight of young mouses Per nest; the average weight of the female mouse after the delivery the rate of the micronucleus of PCE of mouse bone marrow the rate of the sperm-head abnormality the serum cholesterol concentration. In these experimental conditions. we could consider tentatively the colour TV radiation haven't got significative a influence on genetic effects and female reproductive system.