甲亢甲减住院比与居民环境碘摄入量关系
Correlation between hospitalization ratio of hyperthyroidism vs hypothyroidism and environmental iodine intake:a retrospective study
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摘要: 目的 回顾调查甲状腺功能亢进症(甲亢)与甲状腺功能减退症(甲减)住院比率(甲亢甲减比)和环境碘摄入量的动态趋势。方法 回顾性调查1991-2004年江苏省常州市区居民甲亢和甲减的住院病例、食盐碘含量和环境碘摄入量有关数据资料,所得的资料用描述流行病学方法进行分析。结果 14年甲亢住院病例2 625例,甲减住院病例286例;全民食盐加碘(UIS)前,甲亢甲减住院比平均水平为4.3,UIS后升高到10.7,其峰值为19.6;食盐碘含量由USI前<5 mg/kg提高到USI后的>27.7 mg/kg,推算环境碘摄入量由USI前71.6μg/d增加到USI后的>209.0μg/d。结论 甲亢甲减住院比的增加可能与环境碘摄入量增加有关,可作为评估环境碘摄入量变化情况的参考依据。Abstract: Objective To explore the correlation between hyperthyroidism vs hypothyroidism hospitalization ratio(HHHR)and environmental iodine intake.Methods Hyperthyroidism and hypothyroidism hospitalization records,data on salt and environmental iodine intake were collected retrospectively among urban residents of Changzhou city during the period of 1991 to 2004.The data were analyzed with descriptive epidemiological method.Results Totally 2 625 hyperthyroidism and 286 hypothyroidism hospitalization cases were investigated.The HHHR was 4.3 before the universal salt iodization(USI) and increased to 10.7 after USI with a peak value of 19.6.The iodine content of salt was less than 5mg/kg before USI and was 27.7 mg/kg after USI.The environmental iodine intake was increased from 71.6μg/d to 209.0μg/d after USI.Conclusion The increase of HHHR is probably related to the increase of environmental iodine intake.HHHR can be used as the reference for the evaluation of environmental iodine intake.
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