Prevalence of Alzheimer’s disease among residents of Fulaerji district of Qigihar city,Heilongjiang province
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摘要: 目的 探讨黑龙江省齐齐哈尔市富拉尔基区老年性痴呆(AD)的流行病学特点及分布规律。方法采用分层多级整群抽样方法确定调查对象,调查采用筛查和临床诊断两阶段法,筛查阶段采用简易智能精神状态量表(MMSE)和日常生活能力量表(ADL)进行测试,临床诊断阶段根据病史、临床体格检查、神经心理测验作出评定,诊断采用DSM-IV和NINCDS-ADRDA的标准。结果 3 698名≥60岁老年人中,老年AD患者87例,患病率为2.4%,其中轻型占59.77%,中型占24.14%,重型占16.09%;AD患病率女性为2.92%,男性为1.83%,女性患病率高于男性,差异有统计学意义(χ2=4.79,P<0.05);AD的患病率随着年龄的增加而升高(Z=7.90,P<0.01);文化程度越低老年性痴呆的患病率越高(Z=-3.18,P<0.01);农村AD患病率高于城市,差异无统计学意义(χ2=0.77,P>0.05)。结论 富拉尔基区老年性痴呆女性的患病率高于男性;患病率随着年龄的升高增加;文化程度越低患病率越高。
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关键词:
- 老年性痴呆 /
- 患病率 /
- 简易智能精神状态量表 /
- 日常生活能力
Abstract: To explore the epidemiological characteristics and distribution of Alzheimer's disease(AD) among residents of Fulaerji district of Qiqihar city,Heilongjiang province. Methods Stratified mulitstage cluster sampling method was adopted in the survey.The investigation included screening and clinical diagnosis.Mini Mental-State Examination(MMSE)and activites of daily living(ADL)were used in the screening.The diagnosis was made based on clinical history,clinical examination,neuropsychological testing according to the criteria of Diagnostic and Statistical of Mental Disorder,4th ed(DSM-IV)and the National Institute of Neurologic,Communicative Disorders and Stroke-AD and Related Disorders Association(NINCDS-ADRDA). Results Among 3 698 elder persons aged 60 years or over,87 AD patients were identified with a prevalence rate of 2.4%,of which 59.77%,24.14%,and 16.09% were mild,moderate,and severe cases.The prevalence rate was 2.92% for women and 1.83% for men with a significant difference(χ2=4.79,P<0.05). The AD prevalence rate increased with increment of age(Z=7.90,P<0.01).The residents with lower education had a higher AD prevalence rate(Z=-3.18,P<0.01). Conclusion AD prevalence in the females is higher than in the male and the prevalence is positively correlated with the increment of age and negatively with education level among the residents in Fularji district of Qigihar city,Heilongjiang province.-
Key words:
- Alzheimer’s disease /
- prevalence /
- MMSE /
- ADL
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