Abstract: Objective To explore the concentration of serum uric acid(SUA)and its association with metabolic syndrome(MS)and its components in rural residents of Yanbian area. Methods A cross-sectional survey was conducted and concentration of SUA and the indexes associated MS were measured in 4 771 rural residents(1 996 males aged 49.9±11.1 years,2 775 females aged 50.3±11.5 years).MS was diagnosed according to the criteria of "Prevention and Treatment of Blood Lipid Abnormality in Chinese Adult". Results Logistic regression analyses showed that MS and its all components were significantly associated with concentrations of SUA after adjusting for sex,race,age,smoking,and alcohol drinking and the prevalence of MS and its components increased with the increment of SUA in model A.There were significant associations between the components(except hyperglycemia)of MS and the concentration of SUA after adjusting for the same set of variables in model A plus the other components of MS in model B.The same results were showed after adjusting for the same set of variables in model B plus general obesity.The general obesity was significantly associated with the concentration of SUA after adjusting for the same set of variables in model A plus all components of MS.The concentrations of SUA were significantly higher among the people with MS than those without MS(F=170.3,P=0.000)and SUA concentration increased along with the number of MS conponent(F=200.0,P=0.000). Conclusion Among rural residents of Yanbian area,concentration of SUA is strongly associated with the prevalence of MS and its components and increases along with the number of MS component.General obesity is significantly associated with SUA concentration.