目的 了解广西壮族自治区艾滋病患者国际人类免疫缺陷病毒相关性痴呆量表(IHDS)评分的影响因素,为采取相应干预措施提供参考依据。方法随机抽取南宁市第四人民医院2010年11月-2011年3月收治入院的100例年龄<65周岁HIV血清阳性患者进行IHDS问卷调查。结果 艾滋病患者IHDS得分为(8.06±1.81)分;不同特征艾滋病患者IHDS得分比较,≤50岁患者得分为(8.79±1.94)分,高于51～64岁患者的(8.04±2.03)分(t=2.590,P=0.010);汉族患者得分为(9.56±1.70)分,高于壮族患者的(8.93±1.80)分(t=-9.329,P=0.041);小学未毕业患者得分为(7.33±1.37)分,低于小学毕业以上患者的(9.49±1.62)分(t=-7.861,P=0.000);饮酒患者得分为(8.41±1.54)分,低于非饮酒患者的(9.27±1.83)分(t=3.031,P=0.030);男性与女性患者得分分别为(8.92±1.81)和(9.27±1.75)分,吸烟与非吸烟患者得分分别为(8.91±1.60)和(9.15±1.93)分,不同性别、吸烟状况患者得分间差异均无统计学意义(P>0.05);多元线性Logistic回归分析结果表明,年龄越大、饮酒越多的艾滋病患者IHDS得分越低;受教育程度越高的艾滋病患者IHDS得分越高。结论 年龄、文化程度和饮酒状况是艾滋病患者IHDS量表评分的主要影响因素。
Objective To assess the influence factors of International HIV-Associated Dementia Scale(IHDS)among AIDS patients in Guangxi Zhuang Autonomous Region and to provide eveidence for specific intervention. Methods From November 2010 to March 2011,100 human immunodeficiency virus(HIV)positive patients aged＜65 years were selected, excluding the patients with nervous system infection,cerebrovascular disease,major depression,and alcohol and substance abuse,from the Fourth Peoplies Hospital of Nanning City and surveyed with IHDS and Mini-Mental State Examination (MMSE)by trained neurolegists. Results The average IHDS score was 8.06±1.81 among the patients.The score of the patients equal or less than 50 years old was higher than that of 51-64 years old(9.79±1.94 vs 8.04±2.03;t=2.590, P=0.010).The score of the Han patients was higher thant that of Zhuang patients(9.56±1.70 vs 8.93±1.80; t=-9.329,P=0.041).The patients with the education under primary school had a lower score than those with the education equal or higher than primary school(7.33±1.37 vs 9.49±1.62;t=-7.861,P=0.000).Compared with the patients without history of alcohol drinking,the patients with alcohol drinking showed lower IHDS score(8.41±1.54 vs 9.27±1.83;t=3.301,P=0.030).There were no differences in the scores betweeen the ptients of different gender and smoking status(P>0.05 for all).The results of multivariate logistic regression showed that the age and the amount of alcohol consumption were negatively associated with and the education level was positively assciated with the IHDS score among the patients. Conclusion Age,educational level,alcohol consumption are major infulence factors of IHDS score.