Abstract: Objective To investigate the distribution of gamma-glutamyl transferase(GGT)and its correlated factors in rural men of Yanbian area. Methods A cross-sectional study was carried out in 2 001 residents aged 30-70 years. Results The level of the natural logarithm GGT among Korean men(3.55±0.86)was significantly higher than among Han men(3.27±0.72,F=69.366;P<0.000),and the prevalence of GGT disorder in Korean men(25.5%, 260/1 018)was significantly higher than in Han men(13.2%,130/983,χ_MH²=51.408;P<0.000).Single factor analyses revealed that age(χ_k²=18.788,P<0.01),education level(χ_k²=8.387,P<0.01),drinking and smoking (χ_k趋势²=33.876,P<0.000;χ_H趋势²=30.527,P<0.000),hypertension(χ_k²=13.922,P<0.000;χ_H²=16.629, P<0.000),isolated diastolic hypertension(IDH)(χ_k²=9.363,P<0.01;χ_H²=8.219,P<0.01)and systolic hypertension (SDH)(χ_k²=11.276,P<0.01;χ_H²=14.422,P<0.000)were correlated factors for GGT disorder;multiple factor analyses showed that nationality(Korean),age,alcohol drinking,hypertension,SDH,IDH,and isolated systolic hypertension (ISH)were correlated factors for GGT disorder(P<0.05),and a dose-response relationship was observed between GGT disorder and alcohol drinking. Conclusion The prevalence of GGT disorder had significant ethnic difference.The prevalence of GGT disorder was positively correlated with age,alcohol drinking,hypertension,SDH,IDH,and ISH(P<0.05) among men in the area,and dose-response relationship was sobserved between GGT disorder and alcohol drinking.